Generic Name: Bromazepam 3mg
Manufacturer/Distributor: Square Pharmaceuticals Ltd.
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Indications of Laxyl Tablet
Emotional disturbance: Acute tension and anxiety states, difficulties in interpersonal contact. agitation, insomnia, anxious and agitated depressive reactions.
Functional disturbance in the cardiovascular and respiratory systems: Pseudoangina pectoris, precordial anxiety, tachycardia, monogenic hypertension, dyspnea, and hyperventilation.
ln the gastrointestinal system: irritable bowel syndrome, epigastric pain, spasms, bloating diarrhea, etc.
ln the genitourinary system: Frequency, irritable bladder, and dysmenorrheal
Pharmacology of Laxyl Tablet
Laxyl', Bromazepam, is rapidly absorbed from the gastrointestinal tract. Peak plasma concentrations are usually reached within two hours of oral administration of bromazepam. Steady-state plasma concentrations are reached in around five to nine days. Bromazepam is metabolized in the liver, Quantitatively, two metabolites predominate 3' hydroxy - bromazepam and"2 - (2 - amino - 5 - bromo - 3 hydroxy benzoyl) pyridine. Metabolites of Laxyl' {Bromazepam) do not contribute significantly to the effects of the drug.
Dosage & Administration of Laxyl Tablet
The optimum dosage and frequency of administration of Bromazepam should be based on the individual patient, the severity of symptoms, and previous psychotropic drug history. The usual dosage in general practice is from 3 mg to 1 8 mg daily in divided doses. ln exceptional circumstances, in hospitalized patients, up to the maximum daily dosage of 60 mg, in divided doses, may be given. Use in the elderly: Elderly patients are more sensitive to the actions of Bromazepam. Doses should not exceed half of those normally recommended. The lowest dose which can control symptoms should be used. Treatment should not be continued at the full dose beyond four weeks. Long-term chronic use is not recommended treatment should always be tapered off gradually. Patients who have taken benzodiazepines for a prolonged time may require a longer period during which doses are reduced.5pecialist help may be appropriate. Use in children: Bromazepam is not recommended for pediatric use. Bromazepam tablets are for oral administration.
Interaction of Laxyl Tablet
Bromazepam's sedative effects may be increased when coupled with other centrally active medications. Antidepressants, hypnotics, opioids, antipsychotics, sedatives, antiepileptic medicines, sedative antihistamines, and anesthetics are examples of these medications. Cimetidine may extend bromazepam's elimination half-life when taken together. Bromazepam should not be used with alcohol because the sedative effect of bromazepam may be amplified by the alcohol.
Contraindications
Patients with a known hypersensitivity to bromazepam, severe respiratory insufficiency, severe hepatic insufficiency, or sleep apnea syndrome should not use bromazepam.
Side Effects of Laxyl Tablet
Tiredness, sleepiness, muscular weakness, numbed muscle, decreased alertness, confusion, headache, ataxia, and other common side effects include fatigue, drowsiness, muscle weakness, numbed muscle, reduced alertness, confusion, headache, ataxia, and so on. These side effects are most common at the start of therapy and generally go away after a while. Anterograde amnesia may develop when therapeutic dosages are used.
Pregnancy & Lactation
There is no evidence as to drug safety in human pregnancy, nor is there evidence from animal work that it is free from hazards. Do not use during pregnancy, especially during the first and last trimesters, unless there are compelling reasons The administration of high doses or prolonged administration of low doses of benzodiazepines in the last trimester of pregnancy has been reported to produce irregularities in the fetal heart rate, and hypotonia, poor sucking line-hypothermia intenerate. Benzodiazepines have been detected in breast milk. If possible the use of Bromazepam should be avoided during lactation
Precautions & Warnings
The usage of benzodiazepines and benzodiazepine-like substances may result in physical and psychological dependency on these drugs. This dependency is dosage and treatment-length-dependent; it is also more prevalent in susceptible patients with a history of alcoholism. Once physical dependency has been established, discontinuing therapy will result in withdrawal symptoms. Headache, muscular discomfort, severe anxiety, tension, disorientation, and irritability are some of the symptoms. Because the danger of withdrawal and rebound symptoms increases with sudden termination of therapy, it is suggested that the dosage be gradually reduced. Bromazepam is not indicated as a first-line therapy for insomnia induced by psychotic disease. Driving a car or using machinery should be done with caution.
Storage Conditions
Store below 30" C. Protected from light & moisture' Keep all the medicines out of the reach of children.
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